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IF YOU ARE ‘Diet-Resistant’, Exercise COULD BE Key to WEIGHT REDUCTION

By Dennis Thompson

HealthDay Reporter

MONDAY, Aug. 22, 2022 (HealthDay News) — “You can’t run from the fork.”

It’s a vintage weight-loss saying, reminding people that diet is more important than exercise with regards to shedding pounds.

But is that true for everybody?

New research suggests there is a group of “diet-resistant” individuals who need to workout and monitor what they eat should they want to reduce weight.

Actually, these people should prioritize exercise, since it decreases their fat mass and boosts their muscles’ capability to burn calories, the Canadian study concluded.

We discovered that the slow losers responded far better to exercise compared to the fast losers did,” said senior study author Mary-Ellen Harper. She actually is research chair of mitochondrial bioenergetics at the University of Ottawa.

“Hopefully these findings allows an improved, more personalized approach for adults with obesity that are seeking to shed weight, and especially those who have very great difficulties slimming down,” Harper said.

She noted that previous research shows that the power of muscle cells to burn energy varies widely between people.

Individuals who struggle to shed weight generally have very efficient muscle cells; these cells have become proficient at storing energy instead of burning it away, Harper said.

Actually, sometimes an eating plan will decelerate someone’s metabolism a lot more, said David Creel, a psychologist and registered dietitian in the Bariatric and Metabolic Institute at the Cleveland Clinic.

“Their metabolism reacts to the lower calorie consumption by becoming a lot more efficient,” Creel said. “They’ll not respond aswell because they’re not burning as much calories.”

To see if exercise could change that up, Harper and her colleagues mined clinical data from a lot more than 5,000 people who’d participated in a low-calorie weight-loss program at Ottawa Hospital.

This program restricted visitors to 900 calories each day, but there still was several individuals who lost weight at a lower rate than others.

From those records, the researchers matched 10 “diet-resistant” people who have 10 “diet-sensitive” women, and had all of them be a part of a six-week workout program. The participants were matched predicated on how old they are, weight and BMI, and told to consume as usual.


Participants exercised three times weekly. Each exercise session contains 30 minutes of treadmill walking, accompanied by weightlifting and core weight training.

“We can say for certain from the exercise physiology literature you don’t want to do that much to get health advantages from exercise interventions,” Harper said. “The best benefits are in the low end of the spectral range of exercise.”

The exercise didn’t cause weight reduction in either group, however the workouts decreased fat mass, waist circumference and surplus fat only in the diet-resistant participants.

Diet-resistant people also tended to possess greater improvements within their muscle cell metabolism, researchers discovered. Their muscles began to burn up more calories, even at rest.

One expert said those changes likely could have eventually resulted in weight reduction.

“I believe if the intervention have been longer, there might have been an improvement in weight reduction between your groups,” said Dr. Reshmi Srinath, director of the WEIGHT REDUCTION and Metabolism Management Program at the Icahn School of Medicine at Mount Sinai in NEW YORK

The Canadian research team is currently recruiting for a follow-up study with a more substantial sample size.

Individuals who struggle to shed weight generally have “pear-shaped” obesity, making use of their additional weight in the hips, thighs and butt, instead of “apple-shaped” bodies with unwanted weight around their middle, Harper and Creel said.

Previous studies show that regular exercise is among the best predictors of who’ll have the ability to keep lost weight off.

Creel noted that the exercise in this study was relatively mild, and that folks might experience better still results should they will get between 250 and 300 minutes of exercise weekly.

“We realize that perhaps a more impressive range of exercise is necessary for a lot of to help keep weight off than is necessary just for health and wellness,” said Creel, noting that U.S. guidelines demand 150 minutes of cardio weekly to keep health.

The brand new paper demonstrates exercise may be the key ingredient for those who have trouble slimming down solely through diet, Creel said.


“I believe it’s just important that people recognize that not everyone responds to diet just as,” Creel said. “I believe that helps us sort of eliminate that judgment around those who are maybe struggling in a intervention.”

The brand new study was published recently in the eBioMedicine journal.

More info

The Harvard T.H. Chan School of Public Health has more about exercise and weight control.

SOURCES: Mary-Ellen Harper, PhD, research chair, mitochondrial bioenergetics, University of Ottawa, Canada; David Creel, PhD, RD, psychologist and registered dietitian, Bariatric and Metabolic Institute, Cleveland Clinic, Ohio; Reshmi Srinath, MD, director, WEIGHT REDUCTION and Metabolism Management Program, Icahn School of Medicine at Mount Sinai, NEW YORK; eBioMedicine, Aug. 11, 2022, online


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