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Long COVID Doubles Threat of Some Serious Outcomes in Children, Teens: Study

Aug. 4, 2022 CDC researchers report that children and teenagers with long COVID have about twice the chance to getting serious outcomes, in comparison to others without COVID.

Heart inflammation; a blood coagulum in the lung; or perhaps a blood coagulum in the low leg, thigh, or pelvis were the most typical bad outcomes in a fresh study. Despite the fact that the chance was higher for these plus some other serious events, the entire numbers were small.

“Several conditions were rare or uncommon among children in this analysis, but a good small upsurge in these conditions is notable,” a CDC era stated.

The investigators said their findings stress the significance of COVID-19 vaccination in Americans beneath the age of 18.

The study was published online Thursday in the CDC’s Morbidity and Mortality Weekly Report (MMWR).

Less IS WELL KNOWN About Long COVID in Kids

Lyudmyla Kompaniyets, PhD, and colleagues noted that a lot of research on long COVID up to now has been done in adults, so little information can be acquired concerning the risks to Americans ages 17 and younger.

For more information, they compared post-COVID symptoms and conditions between 781,419 children and teenagers with confirmed COVID-19 to some other 2,344,257 without COVID-19. They viewed medical claims and laboratory data for these children and teenagers from March 1, 2020, through January 31, 2022, to see who got some of 15 specific outcomes associated with long COVID.

Long COVID was thought as a disorder where symptoms that last for or begin at the very least 4 weeks following a COVID diagnosis.

In comparison to kids without history of a COVID-19 diagnosis, the long COVID-19 group was:

  • 101% more prone to have an acute pulmonary embolism (blood coagulum in the lung)
  • 99% more prone to have myocarditis (heart muscle inflammation) or cardiomyopathy (once the heart is weakened and contains trouble pumping blood)
  • 87% more prone to have a venous thromboembolic event (blood coagulum in a vein)
  • 32% more prone to have acute and unspecified renal failure (once the kidneys cant filter waste from your own blood)
  • 23% more prone to have type 1 diabetes

“This report points to the truth that the risks of COVID infection itself, both with regards to the acute effects, MIS-C, along with the long-term effects, are real, are concerning, and so are potentially very serious,” says Stuart Berger, MD, chair of the American Academy of Pediatrics Section on Cardiology and Cardiac Surgery.

MIS-C is multisystem inflammatory syndrome in children, a disorder where many areas of the body become inflamed, that is associated with COVID-19.

“The message that people should eliminate out of this is that people ought to be very thinking about all the ways of prevention for COVID, especially the vaccine,” says Berger, who’s also chief of cardiology in the Department of Pediatrics at Northwestern University Feinberg School of Medicine in Chicago.

A ‘Wake-Up Call’

The analysis findings are “sobering and so are “a reminder of the seriousness of COVID infection,” says Gregory Poland, MD, an infectious disease expert at the Mayo Clinic in Rochester, MN.

“Once you try particular at the much more serious complications from COVID in this young generation, those are life-altering complications which will have consequences and ramifications throughout their lives,” he says.

“I’d take this as a significant wake-up call to parents [at a period when] the immunization rates in youngsters are so pitifully low,” Poland says.


The analysis is suggestive however, not definitive, says Peter Katona, MD, a professor of medicine and infectious diseases expert at the UCLA Fielding School of Public Health.

It’s still prematurily . to draw conclusions about long COVID, including in children, because many questions remain, he says: Should long COVID be thought as symptoms at four weeks or a few months after infection? How can you define brain fog?

Katona and colleagues are studying long COVID intervention among students at UCLA to answer a few of these questions, like the incidence and aftereffect of early intervention.

The analysis had “at the very least seven limitations,” the researchers noted. Included in this was the usage of medical claims data that noted long COVID outcomes however, not how severe these were; some individuals in the no COVID group may have had the condition however, not been diagnosed; and the researchers didn’t adjust for vaccination status.

Poland notes that the analysis was done during surges in COVID variants including Delta and Omicron. Put simply, any long COVID effects associated with newer variants like BA.5 or BA.2.75 are unknown.

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