A scientific development from the Tel Aviv and Haifa Universities may facilitate speedy, objective and accurate diagnosis of individuals experiencing PTSD using saliva samples. Within the study, the researchers characterized the psychological, social and medical ailments around 200 participants, while at exactly the same time collecting saliva samples from their website.
The findings of the study show an average microbial picture in the saliva of veteran soldiers who had experienced combat stress-related reactions (from the initial Lebanon War) and so are currently experiencing post-trauma.
Based on the researchers, these results can help later on to reach a precise and objective diagnosis of individuals experiencing post-trauma, also to develop microbiotic-related medications (linked to the body’s microbial ecology).
This study was published in Molecular Psychiatry.
The analysis was a joint effort by scholars from various fields. It had been led by Professor Illana Gozes and included Professor Noam Shomron, Dr. Shlomo Sragovich and Ph.D. student Guy Shapira, (all from TAU’s Sackler Faculty of Medicine and Sagol School of Neuroscience) along with Prof. Zahava Solomon from TAU’s Gershon Gordon Faculty of Social Sciences, and Prof. Abraham Sagi-Schwartz and Ph.D. student Ella Levert-Levitt from the guts for the analysis of Child Development and the institution of Psychological Sciences at Haifa University. The participants in the analysis came from a more substantial cohort of subjects from the comprehensive four-decade-long study of veterans by Prof. Solomon.
The researchers tested a distinctive band of about 200 Israeli veteran soldiers who had fought in the initial Lebanon War in 1982. The test covered various psychological aspects, including sleep, appetite disorders, guilt, suicidal thoughts, social and spousal support, hostility, satisfaction with life, in addition to issues of demographics, psychopathology, welfare, health insurance and education.
Comparing the outcomes of the subjects’ microbial distribution to the psychological results and their responses to the welfare questionnaires, the researchers from the universities of Tel Aviv and Haifa discovered that people who have PTSD and high psychopathological indications exhibit exactly the same picture of bacteria in the saliva (a distinctive oral microbiotic signature). Based on the researchers, this study is significant for the reason that for the very first time, we would have the ability to diagnose post-trauma by objective criteria and not simply behavioral ones. It really is interesting to notice here that the saliva bacteria of these exposed to polluting of the environment showed a correlation to the picture with PTSD, as the period of time of education showed a protective influence and a reverse picture of the microbial ecology in the saliva.
Prof. Illana Gozes says that “to the very best of our knowledge, this is actually the first depiction of a microbial signature in the saliva among veteran soldiers with PTSD. We were surprised to learn that in regards to a third of the PTSD subjects had never been identified as having post-trauma, so that they never received any recognition from the Ministry of Defense and the state authorities.”
“It should be stressed that as yet, post-trauma diagnosis has been based solely on psychological and psychiatric measures. Because of this study, it might be possible, later on, to utilize objective molecular and biological characteristics to tell apart PSTD sufferers, considering environmental influences. Hopefully that new discovery and the microbial signatures described in this study might promote easier diagnosis of post-traumatic veteran soldiers to allow them to receive appropriate treatment.”
More info: Ella Levert-Levitt et al, Oral microbiota signatures in post-traumatic stress disorder (PTSD) veterans, Molecular Psychiatry (2022). DOI: 10.1038/s41380-022-01704-6
Citation: Presence of certain bacteria in saliva might indicate PTSD in veteran soldiers (2022, August 10) retrieved 10 August 2022 from https://medicalxpress.com/news/2022-08-presence-bacteria-saliva-ptsd-veteran.html
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